Aloe has been studied a lot, and has potential health benefits, but if it reliably made a difference in cancer progression, believe me, dozens of NIH-supported researchers would be making their living off of it by now (as is the case for other botanically derived anti-cancer agents, like Taxol, colchicine, and cyclopamine). I am just trying to understand the chemistry behind why bitter almonds are poisonous but bitter almond extract (presumably) isn't. And ethanol suspensions of benzaldehyde are sold (more cheaply than natural almond extract) as imitation almond extract. I did’t know you could eat apricot pits! Food-grade bitter almond extract does not contain amygdalin, because the crude extract is typically treated with a with a mixture of calcium hydroxide and $\ce{FeSO4}$. A sprinkling of wild plum blossoms (Prunus americana) on my way to lab. The bitter almond molecule amygdalin, which breaks down (left to right) into glucose, glucose, hydrogen cyanide (aka Prussic acid to the classicists), and benzaldehyde. All rice noodles and rice paper wraps are gluten-free as they are made wholly from rice. Grocery store almonds, or sweet almonds, contain a small amount of cyanide, but not enough to poison you. But as we say in science, n=1, and it’s hard to evaluate without controls, blinding, and statistical power. Typically, any cyanide taken in by your body will be eliminated within 24 hours, so the daily intake of sweet almonds is not only safe but encouraged, thanks to their many nutrients and health benefits. It’s also possible that different manufacturers may use different syntheses. by John Staughton (BASc, BFA) What I would recommend is cultivating a good relationship with your doctor, and your oncologist (and seek second opinions). Because of a difference in a recessive gene called Sweet kernal [Sk], less amygdalin is present in nonbitter (or sweet) almond than bitter almond. Prunasin hydrolases during fruit development in sweet and bitter almonds, Why “Natural” isn’t always better: almond extract and cyanide, Better Homes and Gardens’ Cheesecake Supreme recipe, Severe cyanide toxicity from ‘vitamin supplements, Everyday Scientist » chemicals ad campaign,, “P” is for poinsettia, pyracantha, and paucity of poisonousness | A bouquet from Mendel,,,, Cherry Banana Ice Cream Shake & Cherry Extract | GAPS Diet Journey. Hey Dawn! Imitation almond extract does not contain amygdalin, but because of the nature of the way amygdalin is made by plants, any natural product that contains amygdalin will also contain cyanide, and even pure amygdalin, when ingested by people, will be hydrolyzed to produce cyanide by your own body. Prunasin hydrolases during fruit development in sweet and bitter almonds PLANT PHYSIOLOGY DOI: 10.1104/pp.111.192021, Start with Better Homes and Gardens’ Cheesecake Supreme recipe. Amygdalin is dangerous and toxic by ingestion. Bitter almonds, however, are the result of a single recessive gene manifesting in these tree nuts. And in bitter almond oil as in a tragic romance, the sweet and the toxic are inextricably entangled. I read that eating a small number (like 10) of bitter almonds can be fatal because of the cyanide. A year (and a lifetime ago) my biopsy showed 7 out of 12 cores with from 10% – 60% cancer, be interesting to see what a biopsy would show now, maybe it only develops when you remove it from the body! 4. Thiocyanate is a sulphur compound -SCN and is essential for an optimally functional mammalian immune system. Found it at Wall to Wall DIY. (And there similarly wasn't evidence that it could be food poisoning from the night before since she ate the same as others. I’ve been eating raw and home roasted almonds daily, all winter long and can’t get enough of the navel orange season… so this has been swirling from the back of my mind now to the front…. Kid social media influencers are promoting junk food and sugar-filled beverages in their YouTube videos, and they are garnering more than a billion views,…, We know that music, particularly musical training can improve the functioning of the brain. Really like to hear your thoughts. I’m hoping this concoction works! What would you suggest as the best “safe” sources for amygdalin. Later she was feeling very nauseated and had a stomach ache. [10] Natural amygdalin has the (R)-configuration at the chiral phenyl center. Hi, I’m interested in amygdalin as an anti cancer agent. In this article, the authors focused on  the enzyme that breaks prunasin down: the glycosidase prunasin hydrolase (PH). If there’s a particular drug or chemical you want more information about, try entering it in the search bar at Medline Plus (also an NIH service): Extra nitty gritty: How an almond ends up sweet or bitter. Well I have this Aloe plant that’s been waiting outside my front door for years, it was 10 days before the scan, how could I not do it? A well-supported, trustworthy online resource that I would recommend about clinical trials and for finding online forums and experts to chat with is the National Institutes of Health’s National Cancer Institute webpage: 2. [Please support Stackprinter with a donation], [ In terms of cyanide content, almond milk is completely safe, as a number of actual almonds used in that beverage are surprisingly low. Thank you so much for your very prompt reply, and for the great info! The whole nuance here is that while a little of a good thing is good, lots of a good thing is bad. Further characterization of these differences may influence the breeding of sweet almonds, where avoiding amygdalin content is the primary goal. This is something I’m still trying to come to terms with, you see I still believe that I have some influence over what’s happening in my body, that state of mind and spirit also play a part, but these things have no place in conventional medical wisdom – if you can’t weigh it and measure it, it doesn’t exist, and if you can’t patent it, it’s not worth investigating – that’s the prison we’ve locked ourselves into. Later, however, it was shown that both cancerous and normal cells contain only trace amounts of beta-glucosidases and similar amounts of rhodanese. These symptoms include: nausea and vomiting, headache, dizziness, cherry red skin color, liver damage, abnormally low blood pressure, droopy upper eyelid, trouble walking due to damaged nerves, fever, mental confusion, coma, and death. I always thought that cyanide smelled like almonds (and vice versa! Centers for Disease Control: “Hydrogen cyanide (AC) is a systemic chemical asphyxiant. Vale was convicted in 2004 for, among other things, fraudulently marketing laetrile as a cancer cure. ), (She does have an allergy to sunflower seeds and certain nuts, but she has no problem eating regular sweet almonds.). Please go seek the advice of an oncologist. Is it safe to apply directly to the skin? [15], Like amygdalin, laetrile is hydrolyzed in the duodenum (alkaline) and in the intestine (enzymatically) to D-glucuronic acid and L-mandelonitrile; the latter hydrolyzes to benzaldehyde and hydrogen cyanide, that in sufficient quantities causes cyanide poisoning. A bowl of rich brown almonds. I didn’t know what Benzaldehyde was, so I did further research and found out it’s something found in bitter almond oil. This provides a natural defense system. Inside the cells of the almond kernel, amygdalin is sequestered from the enzyme that breaks it down: amygdalin hydrolase.